Health Update: Is Pancreatic Cancer Hereditary?

Pancreatic cancer

People mostly ask questions base on is pancreatic cancer hereditary? Our findings revealed that pancreas’ cancer is a genetic disease caused by changes (mutations) in DNA. 

There are two things involved: we inherited it (we are born with them), or we acquired it by developing after we are born.

Also, the inherited changes narrate why cancer of the pancreas runs in some families, then acquired changes can result from either bad luck during cell replication or by exposure to what they called carcinogens.

Is pancreatic cancer hereditary? Research shows that ten percent of pancreatic cancers are hereditary. All these occur as part of rare medical syndromes.

From the ten percent of pancreatic cancers are hereditary. While every ten people with pancreatic cancer, one of them likely has an inherited mutation that increased their risk for developing the disease.

 Know that mutated DNA passes from generation to generation as these called germline mutations and may lead to hereditary pancreatic cancer. It includes:

  • Know your family.
  • Know your risk.
  • Know your plan.

Pancreatic Cancer Risk Factors

Pancreatic cancer1

Risk factors increase your chance of getting a disease such as cancer. In contrast, cancers have different risk factors.

And in some cases, there might be a factor that may decrease your risk of developing cancer or has an unclear effect. 

Here are some of the risk factors known to increase your risk for pancreatic cancer.

Risk factors that can change

  • Tobacco use
  • Being overweight
  • Diabetes
  • Chronic pancreatitis
  • Workplace exposure to certain chemicals

Risk factors that can’t change

  • Age
  • Gender
  • Race
  • Family history
  • Inherited genetic syndromes

What are the odds of getting pancreatic cancer?

The actual average lifetime risk of pancreatic cancer is about 1 in 64. And the chance of an individual getting this cancer can be affected by certain risk factors, which we show above. But statistics show the estimated of people with pancreatic cancer.

This report is from the American Cancer Society’s that estimates for pancreatic cancer in the United States for 2021:

  • More than 60,430 people (31,950 men and 28,480 women) will be diagnosed with pancreatic cancer.
  • More than 48,220 individual (25,270 men and 22,950 women) will die of pancreatic cancer.

While Pancreatic cancer record for about 3% of all cancers in the US and about 7% of all cancer deaths.

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