Mir Hossein Mousavi, the Iran opposition figure and his wife Zahra Rahnavard were examined by a doctor at their home as the couples stay under house arrest for nearly a decade.
It was confirmed that they have tested positive for Covid-19, an opposition website reported on Sunday.
However, their general state of health is good, added the Kaleme site, close to the former prime minister-turned-dissident.
Hossein Mousavi is 79 along with Mehdi Karroubi, 83, were reformist candidates in the controversial election of 2009 which was won by hardliner Mahmoud Ahmadinejad.
Though during the election it was claimed that the vote was rigged, causing months of mass protests dubbed the “Green Movement”.
Karroubi and Mousavi were placed under house arrest without trial in early 2011, with their wives back then.
And hundreds of thousands took to the streets in the capital Tehran, in the biggest challenges to the system since the Islamic revolution of 1979.
But Ayatollah Ali Khamenei, the Iran’s supreme leader called their opposition movement “sedition” and repeatedly demanded the two men repent before receiving any pardon.
But Iranian has been battling with the Middle East’s deadliest novel coronavirus outbreak since February, while they recorded 41,500 deaths out of 762,000 cases.
Anti-Virus restrictions are been considering by the authorities on November 21, after reporting a record of 12,453 cases on Sunday, health ministry reports.